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Innovative medical start-ups: international founders improve cancer therapy

Entrepreneurs with foreign roots, such as Portuguese researcher Prof Dr Angela Moreira Borralho Relógio, think big and internationally. With her start-up TimeTeller, she is developing a test that uses the body's internal clock to optimise cancer therapies. Her aim is to make treatments more effective and better tolerated by administering medication at the right time of day. TimeTeller, which has already won several awards, is working towards certification as a medical device and aims to make its innovative technology available to the general public.

Find the full interview in the Apothekenumschau from the Ausgabe 01. October 2024.

In this episode [Link, Youtube], Nina Ruge talks to Prof Dr Angela Relógio. Together with her colleagues, Relógio investigates the fascinating link between our internal clock and topics such as physical activity, cancer and neurodegeneration. Prof. Dr Relógio, Professor of Systems Biology, introduces us to the exciting world of the internal biological clock, explaining clock-controlled genes and their impact on our health.

This episode, discusses

- What chronobiology is and how it affects our everyday lives.
- What larks, owls, lions, wolves, dolphins and bears have to do with chrono-science
- How knowledge of the circadian clock could revolutionise medicine
- When it's best to exercise
- What to consider when decorating our bathroom
- How we can raise our melatonin levels in the evening
- What other tricks help us to fall asleep and stay asleep
- What jet lag is and how we can get rid of it as quickly as possible

𝗦𝘁𝗮𝗿𝘁𝘂𝗽 𝗠𝗮𝗴𝗮𝘇𝗶𝗻: 𝗧𝗶𝗺𝗲 𝗧𝗲𝗹𝗹𝗲𝗿 𝗺𝗲𝗮𝘀𝘂𝗿𝗲𝘀 𝘁𝗵𝗲 𝗶𝗻𝘁𝗲𝗿𝗻𝗮𝗹 𝗰𝗹𝗼𝗰𝗸

as part of the "ntv Startup Magazin" that reports on creative and innovative business ideas, we had a visit from Silke Böschen and her team.

Silke wanted to know more about the circadian research at the group of Angela Relógio at the MSH Medical School Hamburg and its applications developed at TimeTeller GmbH

The result was a nice short documentary about circadian rhythms, TimeTeller, and some of our future plans including our together work with the Die Techniker Krankenkasse, the largest statutory health insurance in Germany.

A tasty happy end to our chat was the Portuguese Galão at Café Sul, in the Portugiesenviertel in Hamburg with Angela Relógio, Benjamin Dose and the ntv team.

A big thanks to Silke Böschen and her team, the MSH Medical School Hamburg, Deeksha Malhan, Müge Yalçin, Lisa Gottschlich, the medical students and Rainer Petzina , the Rektor of the MSH, and also to the TK and Thomas Ballast, for participating in the documentary.

You find the documentary here: https://www.n-tv.de/mediathek/magazine/startup_news/Time-Teller-hilft-beim-Bestimmen-der-inneren-Uhr-article24949323.html

Wohlbefinden und Genesung im Takt des persönlichen Rhythmus – kann es wirklich so einfach sein? Wir alle wissen: Unsere innere Uhr beeinflusst uns täglich. Doch Prof. Dr. Angela Relógio und ihr Medizin-Start-up „TimeTeller“ gehen noch einen Schritt weiter. Ihre Forschung zeigt, dass der richtige Zeitpunkt der Schlüssel zu effektiverer Behandlung und weniger Nebenwirkungen ist.

In dieser Podcast-Folge sprechen wir mit Angela über ihre bahnbrechende Idee, die biologische Uhr in der Gesundheitsfürsorge zu nutzen. Mit ihrer innovativen Methode hat sie bereits den Gründungspreis+ 2023 gewonnen und wurde zur „Newcomerin des Jahres 2024“ bei den German Startup Awards gekürt.

Von der Forschung bis zur Gründung – sie gibt uns exklusive Einblicke in ihren Weg und diskutiert, ob Berlin oder Hamburg die bessere Start-up-Stadt ist.

Schaltet ein und entdeckt, wie die Zukunft der Medizin im Takt unserer inneren Uhr schlägt!

It was an amazing event yesterday in Berlin! I am extremely honoured for receiving the award! On behalf of TimeTeller GmbH and our outstanding team (Benjamin Dose, Deeksha Malhan, Müge Yalçin, you are the best! 😊), a huge thanks to the Startup-Verband, the Jury members of the GERMAN STARTUP AWARDS, and the all ones who have been working with us during the past months! We are working at high speed to reach the patients, and are most grateful to the Die Techniker for support. We are eager to explore collaborations with our pharma partners, and together develop a new generation of time-optimized medicines.

As part of her cancer research, Prof. Dr. Angela Relógio has been looking for ways to make it easier for patients to take their medication and limit side effects as much as possible. Her solution: the internal clock. To move from basic research to a usable medical product, she founded the company TimeTeller.

Find out in this podcast-episode: The benefits of understanding our own internal clock the potential and limitations of basic research how Angela Relógio perceives working conditions in science and what her day-to-day work as a founder looks like.  You can find her profile here

What an honour to be nominated for the #GSA24 in the category NEWCOMERIN DES JAHRES 2024! On behalf of TimeTeller GmbH, I am super happy! It has been an extremely hardworking first year with the best team in the world and amazing supporters! A huge thanks to the Startup-Verband, and the Jury members of the GERMAN STARTUP AWARDS! See all you at the TIPI AM KANZLERAMT on May 16, 2024. Congratulations to all nominees! It is an honour to be there with all of you! 😃

Researcher Angela Relógio optimises chemotherapy via the internal clock with TimeTeller

Angela Relógio was a guest on the podcast EQUALIZER, a podcast where entrepreneurs share their expertise and experiences to motivate women to start up. In conversation with the hosts Marlis Jahnke and Heidrun Twesten, two experienced entrepreneurs, Angela talks about her professional career, which took her from studying physics in Lisbon, Portugal, her doctorate at the EMBL in Heidelberg, her own research group at the Charité and Humboldt University, her move to the Medical School Hamburg and the founding of TimeTeller 2023 in Hamburg.

In a fascinating discussion, the audience learnt more about the "Circadian Rhythm", the support of mentors like Anne-Mette Jensen, the balance between career and family, and the challenges of funding in research and founding. Angela shared fascinating insights into how the internal clocks in our body cells work and much more in EQUALIZER #51.